Semantic Repository of Genomics Experiments

Sudeshna Das Mass. General Hospital, Harvard Medical School Cambridge, US

Previous efforts
MGED
OBI
EFO Experiment Factor Ontology
Investigation/Study/Assay format (ISA-Tab)

Tried to find a common way of expressing studies in terms of design, data acquisition (OBI), data processing (OBI), data analysis and data interpretation (OBI).

Analysis of Omics Data Using Reverse Causal Reasoning (RCR) in an Integrated Analysis Environment

Dexter Pratt Selventa Cambridge, US

This talk was about an extension of the BEL talk. It represents a longer term look at being able to reason over resources written in BEL and produce reasonable hypotheses about the data and track the users analysis steps and changes to the hypotheses.

Genstruct Technology Platform
extract meaning from large volume of data using causal relations in a transparent manner

The HYP, consolidation of graph of relationships to a causal graph

Rendering Medical Documents in RDF: Strategies and Gotchas

John F. Madden Duke University, Durham, US

voiD: vocabulary of interlinked datasets (http://vocab.deri.ie/void)

Includes provenance, etc.

Using SWObjects to Create and Query RDF Views

Eric Prud'hommeaux Helena Deus W3C Cambridge, US

Slides

Can use SWObjects to easily D2R a database - http://sourceforge.net/apps/mediawiki/swobjects/index.php?title=Connecti...

CBO Resource Index: Ontology-Based Search and Mining of Biomedical Resources

Nigam H. Shah Stanford School of Medicine California, USA

Using either the website at bioportal.bioontology.org or the API at rest.bioontology.org allow for the search of many ontologies and assorted resources. Unfortunately gene lists don't appear to be listed as part of the annotations on the resources. May still be useful.

YouTube introductory video

The Unreasonable Effectiveness of Data

NoSQL: New Possibilities for Distributed Scientific Data Management, Workflow and Collaboration

Mike Miller Assistant Research Professor, U. Washington Founder/Chief Scientist, Cloudant Inc. Boston, USA

CloudAnt is a company primarily concerned with handling large data physics experiments using NoSQL (Not Only SQL in their parlance).

Five types of NoSQL databases:

Semantics for Computational Workflows: A Top Ten List

Dr. Yolanda Gil Associate Director for Research, Intelligent Systems Division, USC/ISI Research Professor of Computer Science Information Sciences Institute University of Southern California, Los Angeles, USA

A lot of the ideas presented here are also goals of the Galaxy team, but they tend to eschew Semantics. Perhaps there is work that can be done/funded here?

Next-generation Architecture for caBIG

Dr. Charles Mead National Cancer Institute Center for Biomedical Informatics and Information Technology (CBIIT) Rockville, USA

caGrid: focus on lowering barrier to entry based a multi-factored evaluation with regards to the group and level of interoperability for the tool to be shared. Several SemWeb proponents are working on the interfaces for 2.0 and they are intending on providing better interfaces to the semantics on the services provided on the grid.

The Phenoscape Knowledgebase: Linking Evolutionary Diversity to Genetic Data Using Phenotype Ontologies

James Balhoff National Evolutionary Synthesis Center Durham, US (NESCent)

Extremely detailed ability to describe phenotypes, probably too much for us. May be worth looking into anyway for our limited phenotype use.

OBO-Edit & Phenote -> Phenex

OBD: Ontology-Based Database

Semantic Analysis and Visualization of Clinical Data

Eric Neumann Clinical Semantics Bedford, US

A presentation on moving from using a reference genome to assembling a unique genome specifically for clinical usage and in support of the development of Personalized Medicine. In addition, the collaboration of Clinical Semantics, BBN and PCAB are interested in tying clinical records to whatever information is available including genomic assemblies and discovered SNPs, etc.

Pages

Subscribe to jesseerdmann.com RSS